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Scientist, Manufacturing

Carlsbad, California
Job Type
15 Oct 2020
Ionis Pharmaceuticals, Inc., one of the 2020 Best Places to Work in San Diego, is located in the North San Diego County city of Carlsbad. Ionis was founded in 1989 and was purposely designed to create a better, more efficient drug discovery platform, establish a new innovation-centered business model, and maximize the value of every medicine created and get it to the people who need it most as quickly and as efficiently as possible.With the RNA molecule as the basis of our novel drug discovery platform, we are targeting an unprecedented range of therapeutic areas. Our antisense therapies are disrupting diseases and changing their course-from the rarest of conditions, to those that impact millions of people. We currently have three commercial products and more than 40 potentially transformative medicines in our pipeline designed to treat a broad range of diseases.Ionis is a challenging, motivating and rewarding environment designed to foster innovation and scientific excellence. Our success is a direct result of our outstanding employees. We are interested in bringing together individuals with different skill sets into this creative environment to be part of a productive team. Join us and experience our unique culture while you develop and expand your career.SCIENTIST, MANUFACTURINGWe are seeking a motivated and versatile individual to join our Manufacturing group in an individual contributor, bench Scientist position. The successful candidate will work closely with other scientists in an interdisciplinary team environment to help optimize our solid-phase oligonucleotide manufacturing process, to make improvements to the synthesis of small molecules that make up our supply chain, and to aid in analytical investigations. The candidate should possess a strong work ethic, excellent communication skills, and a demonstrated record of success in a chemical laboratory setting. RESPONSIBILITIES:Optimize manufacturing and purification processes for the solid-phase synthesis of oligonucleotides and oligonucleotide conjugatesInvestigate raw material and process-related impuritiesDesign and optimize supply chain processesAid in technology transfer to Contract Manufacturing Organizations and partnersParticipate in interdisciplinary project teamsSupport research and development collaborations with Ionis' partnersPresent research to various audiencesAuthor and review research reportsREQUIREMENTS:BS or MS in Chemical Engineering. New graduates with the required experience are encouraged to applyExcellent writing and presentation skillsHands-on experience with standard analytical techniques such as HPLC, LCMS, and NMRDirect experience with a broad range of synthetic and purification techniquesExperience in solid-phase synthesis or polymer chemistry a plusExperience with statistics or DOE a plusStrong interpersonal skillsStrong critical thinking and problem solving skillsAbility to work independently and in teamsFlexibility with job duties in a dynamic environmentAbility to be productive and successful in an intense work environmentExcellent salary and benefits package offered.For more information about Ionis and to apply for this position, please visit our website, . Reference Requisition #IONIS02349NO PHONE CALLS PLEASE. PRINCIPALS ONLY.Ionis Pharmaceuticals, Inc. and all its subsidiaries are proud to be EEO employers.
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  • Job Reference: 182897255-2
  • Date Posted: 15 October 2020
  • Recruiter: Ionis
  • Location: Carlsbad, California
  • Salary: On Application
  • Sector: Manufacturing Operations
  • Job Type: Permanent